Nucleic Acid Isolation System
EXM6000

Nucleic acid isolation system EXM6000 can be widely used in scientific research, clinical diagnosis, disease control and prevention, food safety detection, forensic science and other fields. With the matching reagents kit of Zybio, it can quickly extract nucleic acids from different samples such as whole
blood, serum, plasma, throat swabs, secretions, exfoliated cells, urine, sputum, stool and FFPE tissue. The nucleic acid extraction of 96 samples can be completed in 12 minutes, which can significantly shorten the whole PCR detection time.

Features :

Intelligent and Efficient :

• Real-time view running state of the instrument with built-in LED lamp.
  
• One key to clear errors.

Easy Operation :

• Automatically load the magnetic sleeve.
• 8.4 inch touch screen.
• 5 preset programs for Virus, WB, FFPE, Bacteria, Stool extraction Kit.
• Prefilled reagent kit to reduce the operation process and time.

Excellent Performance :

• Magnetic flux is up to 5500 GS, avoiding the risk of magnetic bead down
• The extraction program is editable and more 50,000
• programs can be stored.
• Only 12 min for extraction of 96 samples

Safety and Reliable :

• Equipped with ventilation facilities and negative pressure exhaust function.
• Equipped with HEPA filter and filter element to ensure the safety of operator.
• Automatic UV sterilization reminder and shutdown

Principle :
The isotion system uses the magnet on the experiment cabin to transfer the magnetic beads adsorbed with nucleic acid to different reagent wells, quickly and repeatedly stir the liquid using the magnetic rod’s tip to make the magnetic beads and liquid evenly mixed. After lysis, nucleic acid adsorption, magnetic beads transfer, wash and elution, high-purity nucleic acid product are finally obtained. The extracted and puried nucleic acid can used in the following PCR amplification detection and construction of second generation sequencing library.

Operations :

• Step1.
          Confirm the extraction program to be uesd, number of samples and sample type.
• Step2.
  

                    Add samples to the pre-filled reagents kit and then load it into the instrument.

• Step3.
          Run the extraction program
  

Performance :

• Linearity :
  Dilute HBV sample at a concentration of 107 IU/ ml 10 fold to the concentration of 106, 105, 104, 103 IU/ ml, and then analyze via qPCR after extraction, linearly dependent coefficient R2=0.9999
• Precision :
  Extract WHO reference (NIBSC code:10/ 264) of HBV at a concentration of 500 IU/ mL 32 times repeatedly, and then analyze via qPCR, CV<= 0.56%
• Sensitivity :
  Extract WHO reference (NIBSC code:10/ 264) of HBV at a concentration of 10 IU/ mL 32 times repeatedly, and then analyze via qPCR, detection rate 20/ 20

Product Details :