BE2100 Sensor - Non-Invasive Biomass Monitoring System

Product Details : 

BE2100 Sensor: Industry Leading, Non-Invasive Biomass Monitoring System

• The BE2100 is an industry-leading, non-invasive biomass monitoring system designed for use in both research laboratory and industrial environments. It provides continuous, real time, and online biomass measurements of your fermentation culture. The sensor is easily secured to the outside of a variety of different fermentor types, from small glass vessels to large stainless steel vessels with glass viewing ports. Since no immersion port is required, the need for sensor sterilization is also eliminated.

Real-time, Online Monitoring

• The BE2100 Biomass Monitoring System consists of a sensor that attaches to a fermentor or bioreactor, and one of three options to control the sensor: a BE2100 base unit (single sensor), a multiplexing BE2100 Base Unit (up to 4 sensors), or the BE|USB (direct USB adapter for single sensor), all of which interface with the included software, providing the user intuitive controls and the ability to track the progress of fermentation in real time. The software can calibrate the sensor output to any desired units (OD, g/L, cells/mL, etc.) as well as track important events during the fermentation. The BE2100 and BE2400 base units comes equipped with serial RS-232, USB and 4-20 mA analog outputs and can function as a stand-alone device or can be controlled through software via RS-232 or USB, enabling straightforward integration into a fermentor control system.
  

Ultra-Wide Linear Range

• Most immersion probe methods are limited in the range of biomass growth they measure. The BE2100 sensor on the other hand employs a novel method of optical monitoring that responds linearly to biomass over a very wide range of growth: from less than 0.1 to greater than 300 OD units.
  

How it Works

• Traditional optical biomass probes rely on a single emitter-detector, resulting in a sensitivity to biomass that is highly non-linear and limited in range. The BE2100 sensor employs an array of infra-red lasers and detectors. Each of the laser-detector pairs in the array is sensitive to a different range of biomass changes. The BE2100 advantage is conferred by combining the signals from each of these pairs in a manner that linearizes its response to biomass changes over a very wide dynamic range.
  

Options for Connecting one or more BE2100 Sensors

• The BE2100 base unit and BE|USB can each accommodate one BE2100 sensor, whereas the BE2400 can accommodate up to four sensors. The diagram below outlines the connectivity options for BE2100 sensors.
  

Advantages

• Widest linear range – from <0.1 to >300 OD units – of any biomass monitor
• Automated, continuous, real-time, online OD measurements
  
• Measures through fermentor wall or viewing port – attaches to outside of vessel
  
• Works well for both fermentation and cell culture
• No immersion port required – avoids fouling and contamination
  
• Lowest total cost of ownership of any biomass monitor currently available
  

BE2100 Sensor Specifications

• BugLab includes our data logging software, with our sensors, at no additional charge.
• The data logging software allows the user intuitive controls and the ability to track the progress of fermentation in real time.
  
• The user experiences real time, online data collection while the sensor is connected to the PC. Profiles such as the type of measurement can be easily customized and uploaded to your sensor through the software, such as g/L, cells/ml, OD, etc.
  
• Events can be logged at any time, such as sampling, glucose input, agitation increase, inoculation and a range of other customizable inputs.
  
• Baseline corrections can be noted as well, at any time during the run, to account for media and substrates.
• New calibration curves can also, be added through the software when correlating the sensor to your off-line spectrophotometer. This is helpful when working with cell types that are highly differentialized in reflectivity, typically from one cell type to another.
  
• The software allows the end user to export the data to an excel file format for additional graphing.
  
• Data log up to 6 sensors at one time via our USB/BE converter or up to 4 sensors at one time with our BE2100 Base unit. If more than 6 sensors are being used, you may install more than one instance of the software onto your PC for additional logging of the sensor.