Phos Tag TM Acrylamide

Product Details :

Phos-tag™ is a functional molecule that binds specifically phosphorylated ions.

It is applicable for the specific separation of phosphorylated proteins (Phos-tag™ Acrylamide) as well as for the detection using western blot (Phos-tag™ Biotin), enrichment, separation and purification (Phos-tag™ Agarose), and MALDI-TOF/MS (Phos-tag™ Mass Analytical Kit).

Methods for determining the phosphorylation status of proteins (i.e., phosphoproteomics) are thus very important with respect to the evaluation of diverse biological and pathological processes.

In 2002, Prof. Koike's group (Hiroshima University) reported that a dinuclear metal complex (i.e., 1,3-bis[bis(pyridin-2-ylmethyl) amino]propan-2-olato dizinc(II) complex) acts as a selective phosphate-binding tag molecule, Phos-tag™ in an aqueous solution at a neutral pH (e.g., Kd = 25 nM for phenyl phosphate dianion, Ph-OPO32-).

Additional Information:

• Item Code: 304-93521
• Production Capacity: 10mg
• Delivery Time: 2-4week
• Packaging Details: 10mg